Laboratory-Grade Precision for Commercial Extraction
Holland Green Science builds equipment for environments where consistency equals credibility. The Xiros Mikro lyophilizer maintains vacuum pressures below 0.1 mBar. The Hephaestus V-series ovens control temperatures within ±1°C. The Preseva freezers prevent temperature fluctuations that degrade trichome integrity. This precision eliminates the variables that cause batch-to-batch inconsistency in artisan operations, delivering repeatable results that scale from small-batch to commercial production.
Complete Laboratory Infrastructure for Solventless Processing
Holland Green Science offers integrated systems that address every critical control point in concentrate production. Each component functions independently but performs optimally when combined into a complete processing environment.
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Freeze-Drying Systems: The Xiros Mikro lyophilizer removes moisture from bubble hash through sublimation, converting ice directly to vapor without the liquid phase that degrades cannabinoids. Operating at sub-zero temperatures throughout 20-24 hour cycles, it preserves 90%+ of volatile monoterpenes compared to 60-70% retention with traditional air-drying. The automated vacuum and temperature controls eliminate manual monitoring while delivering pharmaceutical-grade consistency. Pair with
bubble hash bags and
washing equipment for complete solventless workflows.
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Ultra-Low Temperature Storage: The
Preseva Pagoma and Preseva Plus freezers maintain stable -40°C to -80°C environments for storing fresh-frozen material before washing and preserving finished concentrates post-processing. Consistent cold temperatures prevent ice crystal formation that ruptures trichome heads during storage. The Preseva Plus offers larger capacity for commercial operations processing 50+ lbs weekly, while the Pagoma serves artisan extractors with tighter footprints.
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Vacuum Oven Technology: The
Hephaestus V-series vacuum ovens (models V 094, V 213, V 900) purge residual moisture and solvents from concentrates under controlled negative pressure. This prevents oxidation during the curing process while accelerating evaporation rates. The V 094 handles small-batch artisan production, while the V 900 processes commercial volumes with multi-shelf configurations and programmable temperature ramping.
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Convection Drying Systems: The Hephaestus convection ovens (models 124, 222) provide precise airflow and temperature control for drying plant material, curing edibles, or heat-treating packaging materials. Unlike vacuum ovens that operate under negative pressure, these units circulate filtered air at atmospheric pressure for applications where gentle, even heating matters more than solvent removal.
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Vacuum Pump Infrastructure: Holland Green Science
Premier and Anemos vacuum pumps power both lyophilizers and vacuum ovens with oil-free operation that prevents contamination. The Anemos series delivers higher flow rates for commercial freeze-dryers running continuous cycles, while Premier models serve smaller systems with quieter operation suitable for shared lab spaces.
Matching Equipment Capacity to Processing Volume
Holland Green Science designs equipment across multiple capacity tiers. Selecting appropriately sized systems prevents workflow bottlenecks while avoiding capital expenditure on oversized infrastructure.
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Artisan-Scale Labs (5-20 lbs/week): Small-batch extractors benefit from the compact footprint of the Xiros Mikro lyophilizer paired with the Preseva Pagoma freezer and Hephaestus V 094 vacuum oven. These systems operate on standard 110V power and fit within 10-15 square feet of lab space. This configuration handles weekend extraction runs without requiring dedicated facility infrastructure, making pharmaceutical-grade processing accessible to home-based artisans upgrading from traditional drying methods.
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Mid-Scale Production (20-50 lbs/week): Operations processing multiple strains simultaneously require larger freezer capacity (Preseva Plus) and mid-tier vacuum ovens (Hephaestus V 213) that accommodate multiple trays. At this scale, investing in dedicated
vacuum pumps reduces maintenance frequency and extends equipment life compared to running consumer-grade components at maximum capacity.
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Commercial Facilities (50+ lbs/week): High-volume processors benefit from the Hephaestus V 900 vacuum oven's programmable temperature profiles and the Preseva Plus freezer's walk-in storage capacity. These systems reduce labor costs through automation while delivering the batch consistency necessary for white-label manufacturing and distributor contracts. Commercial operators often run multiple lyophilization cycles daily, making the Anemos vacuum pump series essential for maintaining processing schedules during peak harvest seasons.
Integrating Laboratory Equipment into Extraction Workflows
Proper equipment sequencing and operation maximizes product quality while extending system longevity. These practices optimize Holland Green Science equipment performance.
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Temperature Progression Protocol: Fresh-frozen material must reach -40°C in Preseva freezers for 12+ hours before washing to prevent trichome head rupture. After washing, immediately return separated hash to freezer storage before loading into the Xiros Mikro for lyophilization. This unbroken cold chain preserves monoterpenes that volatilize above -20°C.
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Vacuum System Maintenance: Oil-free Anemos and Premier pumps require less frequent servicing than oil-lubricated alternatives, but monthly inspection of intake filters prevents particulate contamination that reduces pumping speed. Replace pump seals annually in commercial operations running continuous cycles. A properly maintained system pulls vacuum below 0.1 mBar within 15 minutes.
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Cross-Contamination Prevention: Dedicate specific vacuum ovens to particular concentrate types (hash vs. rosin vs. distillate) to prevent terpene cross-contamination. The Hephaestus V-series stainless steel interiors clean easily with isopropyl alcohol between batches, but microscopic residues can affect aromatic profiles in sensitive full-melt products. Commercial labs often maintain separate ovens for different product lines.
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Environmental Controls: Holland Green Science equipment performs optimally in climate-controlled environments maintaining 65-75°F and 40-60% relative humidity. Excessive ambient humidity extends freeze-drying cycles, while temperature fluctuations force vacuum systems to work harder, increasing wear on compressor components. Installing equipment in dedicated HVAC-controlled rooms extends service life and reduces energy consumption.
Holland Green Science represents a commitment to pharmaceutical-grade processing standards in cannabis extraction. For operations ready to move beyond artisan techniques to scalable, audit-ready production systems, this European laboratory equipment delivers the precision and repeatability that regulatory compliance and premium market positioning demand. Explore the complete lineup across specialized categories:
Freeze Dryers,
Laboratory Ovens, and
Laboratory Freezers.
Frequently Asked Questions
What makes Holland Green Science different from other laboratory equipment brands?
Holland Green Science originates from European pharmaceutical research labs where equipment must meet GMP (Good Manufacturing Practice) standards for biological sample preservation and chemical processing. The brand applies this precision engineering to cannabis extraction equipment, delivering industrial vacuum pumps, medical-grade stainless steel construction, and temperature controls accurate to ±1°C. While brands like Harvest Right target home food preservation with consumer-grade components, Holland Green Science builds for commercial laboratories where batch consistency and regulatory compliance determine business viability. The Xiros Mikro lyophilizer and Hephaestus vacuum ovens maintain performance specifications across thousands of cycles, justifying higher initial investment through superior reliability and processing quality.
Can I use the Hephaestus vacuum ovens for both solventless hash and BHO/hydrocarbon extraction?
Yes, the Hephaestus V-series vacuum ovens handle both solventless concentrate curing and residual solvent purging from hydrocarbon extractions. For solventless hash and rosin, the ovens provide low-temperature curing environments (90-110°F) under vacuum that prevent oxidation while allowing cannabinoids to decarboxylate and stabilize. For BHO and live resin, the vacuum accelerates butane and propane evaporation at temperatures below 100°F, preserving terpenes that would volatilize during atmospheric purging. The V 094 suits small-batch artisan production, while the V 900's programmable temperature ramping accommodates commercial workflows requiring precise purge schedules. Always dedicate specific ovens to particular extract types to prevent cross-contamination of terpene profiles.
Do I need to purchase a separate vacuum pump for the Xiros Mikro freeze dryer?
The Xiros Mikro typically includes an integrated vacuum pump system, but commercial operations running continuous cycles benefit from upgrading to dedicated Holland Green Science Anemos or Premier series pumps. These industrial units deliver higher flow rates and longer service intervals than consumer-grade integrated pumps. Oil-free operation prevents contamination from pump lubricants reaching the freeze-drying chamber—critical for full-melt hash where even trace impurities affect vaporization quality. If processing 20+ lbs weekly, investing in a separate Anemos pump reduces maintenance downtime and extends lyophilizer component life. Smaller operations can operate effectively with integrated systems but should budget for pump rebuilds every 2000-3000 hours of operation.
What's the difference between the Preseva Pagoma and Preseva Plus freezers?
The Preseva Pagoma serves artisan-scale operations with compact dimensions suitable for home labs and smaller commercial facilities, typically offering 4-8 cubic feet of storage capacity at -40°C. The Preseva Plus targets commercial processors requiring larger volumes and potentially colder temperatures (-80°C capability), with 12+ cubic feet of interior space for storing multiple strain runs simultaneously. Both models maintain temperature stability within ±2°C to prevent freeze-thaw cycles that rupture trichome heads, but the Plus model includes advanced insulation and more powerful compressors that recover temperature faster after door openings. Choose the Pagoma for processing under 20 lbs weekly, and upgrade to the Plus when workflow demands exceed single-batch storage or when preserving genetics long-term at ultra-low temperatures.
How long does a freeze-drying cycle take in the Xiros Mikro, and can I speed it up?
A complete lyophilization cycle for 1-2 lbs of wet bubble hash runs 20-24 hours, including primary drying (bulk ice sublimation) and secondary drying (residual moisture removal). Cycle time depends on initial moisture content, material density, and pre-freeze temperature. Properly pre-freezing hash to -40°C in a Preseva freezer for 12+ hours before loading reduces total cycle time by 4-6 hours compared to inadequate pre-freezing. Overloading the chamber extends cycles beyond 30 hours and risks heat buildup that degrades cannabinoids. Upgrading to a higher-capacity vacuum pump can reduce cycle time by 10-15% through faster moisture evacuation, but the sublimation process has physical limits—attempting to rush it by raising temperatures defeats the purpose of preserving volatile terpenes.
What maintenance schedule should I follow for Holland Green Science equipment?
Monthly maintenance includes cleaning Xiros Mikro condenser coils, inspecting vacuum pump intake filters, and checking Hephaestus oven door seals for compression. Quarterly tasks involve vacuum pump seal inspection and Preseva freezer condenser coil cleaning. Annual servicing requires replacing Xiros Mikro door gaskets, vacuum pump diaphragms (oil-free models), and recalibrating Hephaestus oven temperature sensors. The equipment includes automated diagnostics that alert operators to maintenance needs before failures occur. Budget 2-4 hours monthly for preventive maintenance in commercial operations. Proper maintenance extends equipment life beyond 10 years while maintaining pharmaceutical-grade performance. Holland Green Science components use standardized parts available through laboratory equipment suppliers, unlike consumer brands with proprietary components requiring manufacturer-direct replacement.
Is Holland Green Science equipment worth the investment for small-batch home extractors?
Home extractors processing 5-10 lbs monthly who prioritize maximum terpene preservation and full-melt quality will recover the Xiros Mikro investment through superior concentrate grading. Freeze-dried hash commands 2-3x premiums over air-dried material in connoisseur markets, and the 20-24 hour processing time beats 7-14 day air-drying periods. However, extractors focused purely on personal consumption may find traditional air-drying adequate despite lower terpene retention. The value proposition strengthens when building a complete Holland Green Science system—pairing the Xiros Mikro with a Preseva Pagoma freezer and Hephaestus V 094 oven creates a pharmaceutical-grade processing environment that scales easily when transitioning from home production to commercial licensing.
Can Holland Green Science equipment handle both cannabis extraction and other laboratory applications?
Yes, Holland Green Science builds multi-purpose laboratory equipment that serves mycology research, pharmaceutical sample preparation, botanical extraction, and food science applications beyond cannabis processing. The Xiros Mikro lyophilizes mushroom cultures, herbal tinctures, and biological samples. Hephaestus vacuum ovens cure specialty foods, dry botanical specimens, and degass epoxy resins. Preseva freezers store research samples, preserve genetics, and maintain biological materials. This versatility protects your investment if pivoting business focus or operating in jurisdictions with evolving cannabis regulations. The pharmaceutical-grade construction and GMP-compliant materials also position equipment for licensed facilities requiring regulatory approval and third-party auditing.
